The study proposed herein has goals that are threefold: (1) characterize PM2.5, solar insolation and land surface temperature using NASA satellite observations, EPA ground level monitor data and North American Regional Reanalysis (NARR) data products on a national scale; (2) link these data with public health data from the REasons for Geographic And Racial Differences in Stroke (REGARDS) national cohort study and determine whether these environmental risk factors are related to cognitive decline; and (3) disseminate the environmental datasets and public health linkage analyses to end-users for decision making through the Centers for Disease Control and Prevention (CDC) Wide-ranging Online Data for Epidemiologic Research (WONDER) system. CDC WONDER furthers CDC's mission of health promotion and disease prevention by speeding and simplifying access to public health information for state and local health departments, the Public Health Service, and the academic public health community. CDC WONDER is used in decision making, priority setting, program evaluation, public health research, and resource allocation. This study directly addresses the public health focus of NASA's Applied Sciences Program, utilizing NASA Earth Sciences products, by addressing issues of environmental health to enhance public health decision making. This study will address concerns expressed in the NRC Decadal Survey regarding the need for continued work to firmly establish the predictive relationships between remotely-sensed environmental data and patterns of environment-related health effects. In addition, the linkage of these data with the CDC WONDER system substantially expands public access to NASA data, making their use by a wide range of decision makers feasible. By successful completion of this research, decision-making activities, including policy making and clinical decision making, can be affected through utilization of the data products and analyses provided on the CDC WONDER system.